TH
EN
 
 
Plant Biotechnology

Supaart Sirikantaramas, Assistant Professor, Ph.D.

B.Sc., Chulalongkorn University
M.Sc. Kyushu University, Japan
Ph.D.
,
Kyushu University, Japan

Office: Room 515/3, Science 10 Building
Phone: 662-218-5425
Fax:      662-218-5418
Email:
Supaart.S@chula.ac.th

Research

  1. Molecular cloning and characterization of rice antimicrobial peptides
  2. Metabolomics of stress-tolerant rice
  3. Enhancing phytonutrients in cruciferous vegetables
  4. Starch biosynthesis in cassava
  5. Engineering cyanobacteria for the production of plant bioactive compounds
 

Professional experiences

May, 1997 – March, 1998 Researcher (Cosmetic products) “Development of liposome-based cosmetic products” Research and Development Division, Biophile Corporation, Thailand

May, 2005 – February, 2008 Post-doctoral researcher, Laboratory of Molecular Biology and Biotechnology, Graduate School of Pharmaceutical Sciences, Chiba University, Japan

April, 2008 – September, 2010 Post-doctoral researcher, Department of Plant Biology and Biotechnology, Faculty of Life Sciences, University of Copenhagen, Denmark

Selected Publications

  1. Boonrueng, C.; Tangpranomkorn, S.; Yazhisai, U.; Sirikantaramas, S.. Molecular cloning, subcellular localization and characterization of two adenylate kinases from cassava, Manihot esculenta Crantz cv. KU50. Journal of Plant Physiology 2016, 204, 66-73.
  2. S. Tantong, O. Pringsulaka, K. Weerawanich, A. Meeprasert, T. Rungrotmongkol, R. Sarnthima, S. Roytrakul, S. Sirikantaramas. Two novel antimicrobial defensins from rice identified by genecoexpression network analyses, Peptides, 2016; 84, 7–16.
  3. Tantong, S.; Incharoensakdi, A.; Sirikantaramas, S.; Lindblad, P.. Potential of Synechocystis PCC 6803 as a novel cyanobacterial chassis for heterologous expression of enzymes in the trans-resveratrol biosynthetic pahtway. Protein Expression and Purification 2016, 121, 163-168.
  4. Sirikantaramas, S.; Meeprasert, A.; Rungrotmongkol, T.; Fuji, H.; Hoshino, T.; Sudo, H.; Yamazaki, M.; Saito, K.. Structural insight of DNA topoisomerases I from camptothecin-producing plants revealed by molecular dynamics simulations. Phytochemistry 2015, 113(17), 50-56.
  5. Sirikantaramas, S.; Yamazaki, M.; Saito, K. Camptothecin: Biosynthesis, biotechnological production and resistance mechanism(s). Advances in Botanical Research 2013, 68, 139-161.
  6. Yamazaki, M., Asano, T., Yamazaki, Y.,Sirikantaramas, S., Sudo, H., Saito, K. (2010) Biosynthetic system of camptothecin: An anticancer plant product. Pure Appl. Chem. 82, 213-218.
  7. Sirikantaramas, S., Yamazaki, Y., Saito, K.(2009) A survival strategy: the coevolution of the camptothecin biosynthetic pathway and self-resistance mechanism. Phytochemistry 70, 1894-1898.
  8. Lehmann, M., Schwarzländer, M., Obata, T., Sirikantaramas, S., Burow, M., Olsen, C.E., Tohge, T., Fricker, M.D., Møller, B.L., Fernie, A.R., Sweetlove, L.J., and Laxa, M. (2009) The metabolic response of Arabidopsis roots to oxidative stress is distinct from that of heterotrophic cells in culture and highlights a complex relationship between the levels of transcripts, metabolites, and flux. Mol. Plant. 2,
    390-406.
  9. Sirikantaramas, S., Yamazaki, M., and Saito, K. (2008) Mechanisms of resistance to self-produced toxic secondary metabolites in plants. Phytochem. Rev.7, 467-477.
  10. Sirikantaramas, S., Yamazaki, M., and Saito, K. (2008) Mutation in topoisomerase I as a self-resistance mechanism coevolved with the production of the anticancer alkaloid camptothecin in plants. Proc. Natl.Acad. Sci. USA.105(18), 6782-6786.
  11. Sirikantaramas, S., Asano, T., Sudo, H., Yamazaki, M., and Saito, K. (2007) Transport of camptothecin in hairy roots of Ophiorrhiza pumila. Phytochemistry 68 (22-24), 2881-2886.
  12. Taura, F., Dono, E., Sirikantaramas, S., Yoshimura, K., Shoyama, Y., and Morimoto, S. (2007) Production of tetrahydrocannabinolic acid by the biosynthetic enzyme secreted from transgenic Pichia pastoris. Biochem. Biophys. Res. Commun. 361(3), 675-680.
  13. Taura, F., Sirikantaramas, S., Shoyama, Y., Yoshikai, K., Shoyama, Y., and Morimoto, S. (2007) Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa. FEBS Lett. 581(16), 2929-2934. 9.
  14.  Sirikantaramas, S., Taura, F., Morimoto, S., and Shoyama, Y. (2007) Recent advances in Cannabis sativa research: biosynthetic studies and potential in biotechnology. Curr. Pharm. Biotech. 8(4), 237-243.
  15. Sirikantaramas, S., Asano, T., Sudo, H, Yamazaki, M., and Saito, K. (2007) Camptothecin: Therapeutic potential and biotechnology. Curr. Pharm. Biotech. 8(4), 196-202.
  16. Sirikantaramas, S., Taura, F., Tanaka, Y., Ishikawa, Y., Morimoto, S., and Shoyama, Y. (2005). Tetrahydrocannabinolic acid synthase, the enzyme controlling marijuana psychoactivity, is secreted into the storage cavity of glandular trichome. Plant Cell Physiol. 46(9), 1578-1582.
  17. Sirikantaramas, S., Morimoto, S., Shoyama, Y., Ishikawa, Y., Wada, Y., Shoyama, Y., and Taura, F. (2004). The gene controlling marijuana psychoactivity: molecular cloning and heterologous expression of Δ1-tetrahydrocannabinolic acid synthase from Cannabis sativa L. J. Biol. Chem. 279 (38), 39767-39774.
 
Academic Staff
 

Anchalee   TASSANAKAJON
Alisa   VANGNAI
Aran   INCHAROENSAKDI
Boonyarin   JARASRASSAMEE
Kanoktip   PACKDIBAMRUNG
Kittikhun WANGKANONT
Kuakarun   KRUSONG

Kunlaya   SOMBOONWIWAT
Lerson   TANASUGARN
Manchumas   PROUSOONTORN
Napa   SIWARUNGSON
Nuchanat   WUTIPRADITKUL
Piamsook   PONGSAWASDI
Rath   PICHYANGKURA
Saowarath   JANTARO
Somporn   KAMOLSIRIPICHAIPORN
Suchart   CHANAMA
Supaart   SIRIKANTARAMAS
Surasak CHUNSRIVIROT
Tanakarn   MONSHUPANEE
Thanyada   RUNGROTMONGKOL
Teerapong   BUABOOCHA
Tikamporn   YONGVANICH
Vichien   RIMPHANITCHAYAKIT

 
Department of Biochemistry, fl. 5, Klum Watcharobol Bld. Faculty of Science, Chulalongkorn University, Payathai Road, Patumwan, Bangkok 10330 Thailand Tel: 662-218-5416-7 Fax: 662-218-5418